Nanoscale “cages” made from strands of DNA can encapsulate small-molecule drugs and release them in response to a specific stimulus, McGill University researchers report in a new study.
The research, published online Sept. 1 in Nature Chemistry, marks a step toward the use of biological nanostructures to deliver drugs to diseased cells in patients. The findings could also open up new possibilities for designing DNA-based nanomaterials.
“This research is important for drug delivery, but also for fundamental structural biology and nanotechnology,” says McGill Chemistry professor Hanadi Sleiman, who led the research team.
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